The profile of inhibitory dsRNA accumulation, as demonstrated by northern blot analysis (Fig 4) and RNAseq (Fig 6), showed that both long CYP3-dsRNA and plant-processed CYP3-dsRNA-derived siRNA accumulate in the plant vascular system, though translocation of siRNA seems to be less efficient and thus siRNA concentration at the remote infection sites probably was not high enough to induced SIGS. This evidence concerns the gene PPIF and infection.