APOA1 and preeclampsia: Preeclampsia is characterized by impaired function and disturbance of lipid metabolism, including reduced high density lipoprotein cholesterol and apolipoproteins A1 and B, which are protective for blood vessels, and increased total cholesterol, triglycerides, low density lipoprotein cholesterol and very low density lipoprotein cholesterol, which are destructive to blood vessels.