EGFR and metastatic colorectal cancer: Panitumumab, a fully human monoclonal antibody targeting the epidermal growth factor receptor (EGFR), is effective as monotherapy and in combination with chemotherapy for treatment of patients with metastatic colorectal cancer (mCRC) (Van Cutsem et al, 2007; Douillard et al, 2013; Poulin-Costello et al, 2013; Peeters et al, 2015).