Furthermore, the comparison of different combinations of CD57+ NK cells infiltration between tumor nest and stroma showed that patients with high infiltrating density of CD57+ NK cells in tumor nest and low infiltrating density in tumor stroma had a best OS, while high or low infiltration in both the tumor nest and stroma displayed medium OS respectively, and the patients with low infiltrating density of CD57+ NK cells in tumor nest and high infiltrating density in tumor stroma had a worst OS (median OS: 4.25, 1.95, 1.60 and 0.75 years, P = 0.0014). This evidence concerns the gene B3GAT1 and neoplasm.