CD68 and neoplasm: In addition, after adjusting for gender, age, tumor size, TNM stage and treatment, the death risk was increased by 48.8% (HR = 1.488, 95% CI: 0.996–2.221, P = 0.052) in patients with high infiltrating density of CD68+ macrophages in the tumor nest compared with patients with low infiltrating density of these macrophages, as shown in Table 6.