BIRC5 and neuroblastoma: The notion that YM155-induced survivin depletion is not a consequence of DNA damage induction in neuroblastoma cells was further supported by data showing that irradiation-induced DNA damage did not decrease the survivin levels in UKF-NB-3 cells but rather resulted in enhanced survivin levels, both in the presence and in the absence of p53 (Figure 6a and Supplementary Figure 6).