TP53 and glioblastoma: They include known GBM-related pathways, such as apoptosis36, cell cycle37, cytokine-cytokine receptor interaction38, ErbB signaling pathway39, JAK-STAT signaling pathway40, MAPK and mTOR signaling pathway41, p53 signaling pathway42, TGF-beta signaling pathway43, VEGF signaling pathway44, and Wnt signaling pathway45.