The performance of BATF2 as single transcriptional biomarker in these cohorts was comparable to the performance of other recently reported transcriptional signatures of active TB based on 4 genes (GBP1, ID3, P2RY14, and IFITM3) (17) or 3 genes (GBP5, DUSP3, and KLF2) (18). This evidence concerns the gene KLF2 and tuberculosis.