LRRC25 and campylobacteriosis: In the United Kingdom and other high-income countries, the impact of RT-PCR failures observed in this study would be limited because (i) C. coli accounts for a small proportion of human campylobacteriosis cases (12), (ii) the RT-PCR result was unaffected for the majority of isolates with introgressed mapA alleles, and (iii) clade 2 and 3 C. coli strains rarely cause human disease (54).