Interestingly, we observed that all tumor cells showed the complete loss of nuclear staining for SMARCB1 in both the organoid and non-adhesive areas with rhabdoid cells compared with the ubiquitous expression of SMARCB1 in surrounding normal tissue (Fig. 2e, f), indicating a renal malignant rhabdoid tumor. This evidence concerns the gene SMARCB1 and rhabdoid tumor.