The results obtained revealed that the ZNF216 mRNA was variably expressed among the cell lines (Figure 1A) with the highest level of expression found in melanoma cell line MDA-MB4-35 weakly expressing EGFR and the lowest levels shown in breast carcinoma cell lines T-47D and HBL-100 moderately expressing EGFR mRNA [32]. This evidence concerns the gene EGFR and melanoma.