LCN2 and endometrial cancer: According to numerous studies in which LCN2 was quantitated by immunological methods such as immunohistochemistry, ELISA, gel zymography, and Western blots in urine, LCN2 has been proposed as an early marker of bladder, brain and endometrial cancer (Monier et al., 2000, 2002; Roy et al., 2008; Smith et al., 2008; Mannelqvist et al., 2012).