Similarly, higher SR-BI expression in breast cancer tissue was associated with increased disease aggressiveness and patient mortality (Yuan et al., 2016), while RNA microarrays of samples from patients with chronic myeloid leukemia identified a six gene profile including SCARB1 (the gene encoding for SR-BI) that discriminated early and late-stage disease (Oehler et al., 2009). This evidence concerns the gene SCARB1 and breast carcinoma.