KCNJ10 and myeloid sarcoma: Due to technical difficulties including the impact of high-order structure formation of the KIR4.1 channel complex and post translational modifications on KIR4.1-antibody binding, Chastre et al. concluded that further studies are required to clarify the presence of KIR4.1 autoantibodies in MS, including investigations through cooperative sharing of specimens (Chastre et al., 2016).