While c-myc-3’RR mice developed non-activated CD43- BL, a wider pattern of lymphomas occurred in c-myc-3’RR/p53- mice including CD43- BL, CD43+ BL, MCL-like lymphoma (IgM+CD5+CD43+CD23- cells) and PCL (IgM-/lowIgD-/lowCD138+ cells) [27, 28]. This evidence concerns the gene CD5 and mantle cell lymphoma.