Furthermore, we detected the VEGF/EGFR expression in CRC cell lines and found that VEGF/EGFR expression in the highly invasive CRC cell lines (SW620 and LoVo) were evidently up-regulated than those in the minimally metastatic CRC cell lines (SW480 and HT29) (Fig. 2). Here, VEGFA is linked to colorectal carcinoma.