Two of these genes, branched‐chain amino acid transaminase 1 (BCAT1) and ikaros family zinc finger protein 1 (IKZF1) may play an important functional role in maintaining a healthy colorectal tissue 20, 21, and both BCAT1 and IKZF1 appear to be involved in tumor growth and invasiveness 21, 22, 23, 24, 25, 26. The gene discussed is IKZF1; the disease is neoplasm.