Moreover, they showed that either recombinant human cytokine CXCL9 (rhCXCL9) or gene transfer of CXCL9 inhibited tumor‐derived angiogenesis, suppressing tumor growth and metastasis, which counteracted the angiogenic role of ELR+ chemokine (such as IL‐8 and epithelial neutrophil activating protein 78) partly 36. This evidence concerns the gene CXCL8 and neoplasm.