DTNBP1 and schizophrenia: The timing of environmental insults during development and specific genetic vulnerability are important considerations in determining susceptibility to neurodevelopmental disorders and could differentially affect the degree to which DTNBP1 mutations impact on structural and functional properties of neuronal cells, circuit connectivity, and overt behavioural phenotypes such as cognition, anxiety, and affective behaviour, leading to heterogeneous clinical phenotypes in schizophrenia [2, 25].