To that end, we co-xenotransplanted primary human monocytes (Mo; the proposed precursors of CD163+ myeloid cells) from healthy blood donors together with human breast cancer cells of the luminal A (MCF-7 or T47D cells) or TN (MDA-MB-231 or SUM-159 cells) subtypes in highly immunodeficient NSG-mice. Here, CD163 is linked to breast cancer.