Therefore, we confirmed our data in mice grafted with TN as compared with luminal patient-derived tumour tissue (PDX), where we could see that more myeloid cells infiltrated the TN tumours, and although the infiltrating myeloid cells were located closer to the borders of the tumours, these areas did show more S100A9 expression and activated fibroblasts (αSMA) in the TN, as compared with the luminal graft. Here, ACTA1 is linked to neoplasm.