APP and Anxiety: Interestingly, wt mice injected with the mix of the two peptides displayed abnormal behavioral phenotypes very similarly to age matched APP/PS1 mice, both in terms of enhanced motor activity, as indicated by the total distance traveled (Fig. 4a), and in terms of increased anxiety levels, as revealed by the longer time spent in the periphery (Fig. 4b) and the shorter time spent in the center (Fig. 4c) of the arena.