KCNJ10 and autosomal dominant cerebellar ataxia: In JRT, PRT and related breeds, the missense mutation c.627C > G in the KCNJ10 (potassium inwardly-rectifying channel, subfamily J, member 10) gene (Transcript XM_545752.4) was found to be strongly associated with spinocerebellar ataxia (SCA) [7, 11].