TNF and uveitis: Furthermore, treatment strategies changed drastically with the upcoming of methotrexate (MTX) around 1990 and later anti-TNFα therapy around the year 2000.[19–22] Also, ophthalmologic screening protocols for patients with JIA were introduced around 1990.[23–25] The objective of this study was to analyze uveitis activity and its complications and visual prognosis in adults with JIA-uveitis and to compare patients with an onset of uveitis before and after the year 1990.