These facts support the expectation that NF-κB is mainly involved in the progression of CXCR2-driven ovarian cancer, leading to augmentation of CXCR2 ligands such as CXCL1-3 and 5–8 followed by proinflammatory tumor microenvironment via CXCR2 axis. Here, NFKB1 is linked to neoplasm.