STAT3 and myelodysplastic syndrome: Also the PB and BM mRNA expression levels of RORγt and STAT-3, transcriptional factors of Th17 cells, were markedly higher in L-MDS patients and lower in H-MDS patients compared to healthy persons, implying that not only the percentage but also the functional and activation state of Th17 cells displayed an expansion in L-MDS and a sag in H-MDS.