MMP13 and fibrodysplasia ossificans progressiva: For instance, Oricula Therapeutics is developing Proto-1 for prevention of hearing loss, Novo Biosciences is developing a metalloproteinase-13 (MMP13) inhibitor for peripheral neuropathy, and La Jolla Pharmaceuticals is developing BMP receptor inhibitors for fibrodysplasia ossificans progressiva (FOP) and other rare diseases.