The apparent modulatory potency of EPs® 7630 on IFN levels, endowed with potent antiviral effects and mediating functional activity of natural killer cells [42], was demonstrated by enhanced IFN-ß synthesis in human MG-63 osteosarcoma cells when superinduced with the viral double-stranded RNA analogue polyinosinic acid: polycytidylic acid [35]. The gene discussed is IFNA1; the disease is osteosarcoma.