This cardiomyopathy associated with a glycogenin-1 mutation but without skeletal muscle weakness differs from the previously described cases who typically had a rather late onset skeletal myopathy without cardiomyopathy (Malfatti et al 2014; Colombo et al 2016; Fanin et al 2015; Luo et al 2015; Akman et al 2016). Here, GYG1 is linked to skeletal muscle disorder.