For instance, IL-10 was shown to suppress Th1 cytokine production by CTCL cells, and malignant CTCL cells impede dendritic cell maturation, as well as activation of benign T cells, in an IL-10-dependent manner, indicating that IL-10 contributes to the suppression of cellular immunity and anti-tumor responses [66–68]. Here, IL10 is linked to primary cutaneous T-cell non-Hodgkin lymphoma.