To assess the effects of AβpE3-42 on neurodegeneration, we expressed AβpE3-42 constitutively in the fly eye using the GMR-GAL4 driver and observed the effect on the organization of the ommatidia, an assay that has been used extensively to characterise fly models of neurodegenerative diseases [35]. The gene discussed is LGALS4; the disease is neurodegenerative disease.