DHCR7-DT and systemic lupus erythematosus: In addition, it must be noted that complement AP abnormalities, genetic or acquired, have been identified in a subset of patients showing susceptibility to systemic lupus erythematosus [5], and particularly frequently in patients with immune complex-mediated MPGN [26] and atypical post-infectious glomerulonephritis [27], the latter showing overlapping features with C3GN [28].