Thus, in an epidemiological study, 2.5 % of control calves had thrombocytopenia and leucocytopenia without clinical signs of BNP [15], and another research group induced subclinical BNP in 20 % of calves after feeding with colostrum from ‘BNP dams’ [23]. The gene discussed is NPPB; the disease is Thrombocytopenia.