IFNG and tuberculosis: The diagnosis of latent tuberculosis (TB) relies on the demonstration of an acquired cell-mediated immune response to Mycobacterium tuberculosis (Mtb) in an otherwise asymptomatic person, either by Tuberculin skin testing (TST) or Interferon gamma release assays (IGRA) (e.g., QuantiFERON®-TB Gold in-tube (QFT-GIT) and T-SPOT.TB) [1].