Likewise, SHIP2 staining intensity follows the same trend with intensity increasing with progressing levels of dysplasia (0.13 ± 0.23, 0.80 ± 0.53, 1.59 ± 0.80 in non-cancerous tissue, dysplasia and CRC respectively, p < 0.01) (Figure 1F). Here, INPPL1 is linked to dysplasia.