However, TLR6−/− mice infected with L. major did show significant differences in lesion size compared to WT mice, with healing occurring earlier resulting in significantly smaller lesions in the later stages of infection (weeks 11–12) (Week 11: U = 2, P = 0.0047; Week 12: U = 0, P = 0.0012) (Fig. 1a). The gene discussed is TLR6; the disease is infection.