IFNG and infection: When the ratio of IFNγ:IL-10 production was calculated, an increased ratio was recorded in TLR6−/− mice when compared to TLR2−/− mice at week 10 p.i., which was almost significant (U = 2, P = 0.064), suggesting that TLR6−/− mice have an enhanced ability to promote a Th1 immune response which is linked to enhanced resistance to infection (Fig. 4c).