In contrast to IL-17A, global IL-17RA immunoreactivity was significantly elevated in cystitis and polyp compared with those of bladder cancer (Fig. 1c and d, p = 0.001 and p = 0.001, respectively), while global IL-17RA immunoreactivity was significantly higher in polyps than those of cystitis (p = 0.015). The gene discussed is IL17RA; the disease is urinary bladder cancer.