IDH1- R132H dominated in diffuse astroctytoma (29/50, 58%) and anaplastic astrocytoma (5/9, 55.6%) compared with in primary GBMs (9/58, 15.5%) (Figure 1A; Table 1, p<0.0001, Chi-Square test). The gene discussed is IDH1; the disease is anaplastic astrocytoma.