More precisely, GLUT1 deficiency may cause a specific syndrome which correlates with hyperactivity and developmental delay [3, 4], RIMS3 is considered to be a novel candidate for autism [5], GRIK3 has also been associated with developmental delay [6], and AGO1/AGO3 may be responsible for neurocognitive deficits [7]. This evidence concerns the gene AGO1 and Global developmental delay.