Other molecules of the IL-1 family (IL-1α, IL-18, IL-1R1, IL-1RA, IL-1RAcP, and ST2L) and molecules associated with inflammasomes (NLRP-1, NLRP-3, NLRC-4, caspase I, and ASC) have been reported to be active in early pregnancy, parturition, preterm labor, preeclampsia, and infection during pregnancy (3, 4, 6). The gene discussed is IL1R1; the disease is preeclampsia.