Upon comparison to the human lung adenocarcinoma cell line, A549, which is known to highly express GRP7810, the high-grade glioma cell lines (Hs 683, T98G, U-373 MG, A172 and U-87 MG) likewise displayed high expression of GRP78 (Fig. 1B). The gene discussed is HSPA5; the disease is central nervous system cancer.