Further inference can also be deduced by the observation that the classes of TRPA1–/– afferent displaying deficits are exactly the same classes of TRPA1+/+ afferent displaying mechanical hypersensitivity after TNBS induced colitis, namely splanchnic mesenteric and serosal afferents and pelvic serosal and mucosal afferents (compare Figure 2, Figure 3 and Figure 4) [21,35,37]. Here, TRPA1 is linked to colitis.