Lp-PLA2, also known as secretory phospholipase A2 group VII (sPLA2-VII) and as platelet activating factor acetylhydrolase (PAF-AH), is widely expressed in cells involved in atherosclerosis, such as macrophages, T-cells, lymphocytes, and mast cells [1,2]. The gene discussed is PLA2G7; the disease is atherosclerosis.