OXT and major depressive disorder: Demitrack and Gold [132] found no significant difference in CSF levels of OXT between MDD and control subjects.Pitts et al., [133] assessed CSF levels of OXT in a heterogeneous population of MDD patients (10 men and nine woman) who were further separated into dexamethasone non-suppressors and suppressors and described a trend towards lower OXT levels in the CSF of dexamethasone suppressors compared with healthy controls.