In the other hand, Dot1l failed to predict tumor outcomes in pT (3+4) group (P<0.001, Figure 3B, 3D), Fuhrman grade (3+4) group (P=0.079, P=0.113, Figure S1B, S1D) and SSIGN/Leibovich (≥4) group (P<0.001, Figure S2B, S2D). Here, DOT1L is linked to neoplasm.