Several studies have also demonstrated that p210 protein fusion region-derived peptides bind to different MHC class-I molecules (A11 ,A0201 ,A3 and B8) and induce CML-specific cytotoxic T lymphocytes (CTL), which can kill CML cells in vitro [20, 22–26]. The gene discussed is EVPL; the disease is chronic myelogenous leukemia, BCR-ABL1 positive.