AREG protein expression of “High” was recorded as 39.30% of the stomach benign tissues in chronic gastritis, 37.93% of the intestinal metaplasia tissues, 30.0% of the low-grade intraepithelial neoplasia tissues, 37.50% of the high-grade intraepithelial neoplasia tissues, and 23.08% of the matched non-tumor tissues. The gene discussed is AREG; the disease is chronic gastritis.