The effects of other potential AhR ligands (or mixtures containing AhR ligands) such as polychlorinated biphenyls (Wahlang et al. 2013, 2014; Shan et al. 2015), cigarette smoke (Mallat and Lotersztajn 2009), and diesel particles (Arciello et al. 2013) have been tested on different mouse models of obesity. The gene discussed is AHR; the disease is obesity due to melanocortin 4 receptor deficiency.