Projecting the 16 overlapping entities onto the protein functional interaction networks using the ReactomeFI revealed network patterns highly enriched in carbohydrate metabolism, Parkinson’s disease, arginine and proline metabolism, oxidative phosphorylation/mitochondrial dysfunction, cellular response to heat stress/neuregulin signalling and tight junction/EPH-Ephrin signaling pathways (Fig 3). This evidence concerns the gene EPHA1 and Parkinson disease.