CCR2 and asthma: Dandona et al. [13] found the elevated expression of CCR-2 as well as IL-4 and MMP-9 asthma mediators in the mononuclear cell fractions from obese and obese/T2D patients which indicated that these cell populations were responsive to chemotaxis by chemotactic cytokines such as MCP-1/CCL-2 and eotaxin.