For example, Yang et al. [119] found that a water-soluble polysaccharide from G. pentaphyllum herb tea (PSGP) indirectly exerted anti-cancer activity against SW-1116 human colorectal adenocarcinoma cells and HT-29 by enhancing the immune response of macrophages with increased TNF-α secretion in a dose-dependent manner. This evidence concerns the gene TNF and cancer.