To address the challenge presented by the emergent nature of some appendicitis cases, we performed a retrospective study in which we considered three factors, a body temperature ≥37.4 °C, C-reactive protein (CRP) level ≥4.7 mg/dl, and fluid collection surrounding the appendix on computed tomography (CT), as potential preoperative factors predictive of complicated appendicitis [5]. Here, CRP is linked to appendicitis.